COST-EFFECTIVENESS ANALYSIS OF ABIRATERONE, DOCETAXEL OR PLACEBO PLUS ANDROGEN DEPRIVATION THERAPY FOR HORMONE-SENSITIVE ADVANCED PROSTATE CANCER

Cost-effectiveness analysis of abiraterone, docetaxel or placebo plus androgen deprivation therapy for hormone-sensitive advanced prostate cancer

ABSTRACT Objective To evaluate the cost-effectiveness of the addition of chemotherapy or abiraterone to androgen deprivation.Methods We developed an analytical model to determine the cost-effectiveness of the addition of docetaxel or abiraterone versus androgen deprivation therapy alone.Direct and indirect costs were included in the model.The effec

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Growth trends of spruce in the Orlické hory Mts.

In 2002, height and diameter growth of spruce was investigated in the Orlické hory Mts.(the Czech Republic).The aim was to confirm and to quantify a growth increase in stands of different age, and to reveal the relation between growth and climate, and level of nitrogen deposition.Stem analyses of ten sample trees of mature spruce stand (average ag

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